Table 7:
GRADE Evidence Profile for Comparison of HBOT and Standard Care on All-Cause Mortality
| Number of Studies (Design) | Risk of Bias | Inconsistency | Indirectness | Imprecision | Publication Bias | Upgrade Considerations | Quality |
|---|---|---|---|---|---|---|---|
| 1 (RCT) | No serious limitations | No serious limitations | No serious limitations | Serious limitations (−1)a | Undetected | No other considerations | ⊕⊕⊕ Moderate |
| 1 (NRCT)34 | No serious limitations | No serious limitations | No serious limitations | Serious limitations (−1)a | Undetected | No other considerations | ⊕ Very Low |
Abbreviations: GRADE, Grading of Recommendations Assessment, Development, and Evaluation; HBOT, hyperbaric oxygen therapy; NRCT, nonrandomized controlled trial; RCT, randomized controlled trial.
a
Wider confidence intervals that, if aligned with true estimate, can either increase or decrease risk of mortality.