Study title: Cost-effectiveness of adjunctive hyperbaric oxygen in the treatment of diabetic ulcers
First author/year: Guo S/2003
Checklist completed by: Brian Chan
APPLICABILITY (relevance to question under review)
Item	Yes/Partly/No/Unclear/NA	Comments
Is the study population similar to the question?	Yes
Are the interventions similar to the question?	Yes
Is the health care system in which the study was conducted similar to the current Ontario context?	No
Was/were the perspective(s) clearly stated, and what were they?	Yes, United States societal
Are estimates of treatment effect from the best available source?	Yes
Are all future costs and outcomes discounted?	Yes	3%
Is the value of health effects expressed in terms of quality-adjusted life years?	Yes
Are costs and outcomes from other sectors fully and appropriately measured and valued?	No
Overall Judgment (directly applicable/partially applicable/not applicable): Partially applicable
Comments Regarding Judgement: From a US private payer perspective.

Source: National Institute for Health and Care Excellence. The guidelines manual: appendices B-I, appendix G: Methodology checklist: economic evaluations [Internet]. London (UK): The Institute; 2012 [cited 2014 Oct 6]. Available from: http://publications.nice.org.uk/the-guidelines-manual-appendices-bi-pmg6b/appendix-g-methodology-checklist-economic-evaluations