Study title: Cost-effectiveness and budget impact of adjunctive hyperbaric oxygen therapy for diabetic foot ulcers
First author/year: Chuck AW/2008
Checklist completed by: Brian Chan
APPLICABILITY (relevance to question under review)
Item	Yes/Partly/No/Unclear/NA	Comments
Is the study population similar to the question?	Yes
Are the interventions similar to the question?	Yes
Is the health care system in which the study was conducted similar to the current Ontario context?	Yes
Was/were the perspective(s) clearly stated and what were they?	Yes, Ministry of Health
Are estimates of treatment effect from the best available source?	Yes
Are all future costs and outcomes discounted?	No
Is the value of health effects expressed in terms of quality-adjusted life years?	Yes
Are costs and outcomes from other sectors fully and appropriately measured and valued?	No
Overall Judgment (directly applicable/partially applicable/not applicable): Directly applicable
Comments Regarding Judgement:

Source: National Institute for Health and Care Excellence. The guidelines manual: appendices B-I, Appendix G: Methodology checklist: economic evaluations [Internet]. London (UK): The Institute; 2012 [cited 2014 Oct 6]. Available from: http://publications.nice.org.uk/the-guidelines-manual-appendices-bi-pmg6b/appendix-g-methodology-checklist-economic-evaluations