Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Functional p53 is required for miR-181a mediated docetaxel resistance. p53-null PC3 cells were transfected with miR-181 mimics or antisense, along with the appropriate controls, and treated with 5 nM docetaxel (DTX). After 48 hours treatment, cell number (A) was determined by Coulter counter and apoptosis (B) was determined by cell death ELISA. Results are presented as means ±SEM of three replicate experiments conducted in duplicate.
