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Voltage-clamp whole-cell recordings were conducted in DH neurons.
Notes: (A) Current was recorded at a holding potential of −70 mV, with 2000 ms pulses between −80 and +50 mV. Neuron was initially recorded in 140 mM external Na+ and then perfused with a solution in which NaCl was completely replaced with the impermeable cation N-methyl-d-glucamine (NMG-Cl). (B) Removal of extracellular Na+ reduces IK in DH neurons. *P<0.05.
Abbreviation: DH, dorsal horn.
