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. 2004 Dec 16;24(1):85–96. doi: 10.1038/sj.emboj.7600500

Figure 6.

Figure 6

CARM1 functions in a gene-specific manner. (A) Quantification of TNFα-stimulated MIP-2, IP-10, MCP-1 and IL-6 transcription Carm1(+/+) MEF cells (filled circles) and Carm1(−/−) MEF cells (empty circles) by real-time PCR. (B) Quantitative ChIP assays with anti-CARM1 antibodies were performed for the indicated genes on TNFα-stimulated Carm1(+/+) (filled circles) and Carm1(−/−) MEF cells (empty circles). (C) Anti-methyl-H3(R17) ChIP assay for the indicated genes on TNFα-stimulated Carm1(+/+) (filled circles) and Carm1(−/−) MEF cells (empty circles). (D) ChIP assays with anti-p65 antibodies were performed for the indicated genes on TNFα-stimulated Carm1(+/+) (filled circles) and Carm1(−/−) MEF cells (empty circles).