Figure 6. Alterations in key lipogenic genes predict overall survival in patients with prostate adenocarcinoma.
A) Genetic and mRNA alteration of key lipogenic genes in patients with neuroendocrine PCa, made publicly available by cBioportal. B) Chart depicting the probability that alterations in the key lipogenic genes co-occur together in patients with CRPC (including both PRAD and NEPC phenotypes) made available by cBioportal. C) Genetic and mRNA alterations of key lipogenic genes in patients with prostate adenocarcinoma (TCGA PRAD, provisional), made publicly available by cBioportal. D) Kaplan-Meier curve depicting overall survival between patients with no genetic alterations (blue line) and patients with genetic alterations (red line) in the key lipogenic proteins. Kaplan-Meier curve was generated via cBioportal. Abbreviations: CRPC = castrate recurrent prostate cancer, NE = neuroendocrine, Adeno = adenocarcinoma.