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. Author manuscript; available in PMC: 2017 May 30.
Published in final edited form as: Methods. 2014 Apr 21;68(3):441–449. doi: 10.1016/j.ymeth.2014.04.011

Figure 5.

Figure 5

Effect of pH on the efficacy of camptothecin. The pH of the 1×M9 buffer in which the liquid exposure was performed was altered. N2 and slx-1 late L4s were exposed to either 500 or 1000 nM CPT or a mock dose of DMSO. Eggs laid from 22–26 hours after the initiation of exposure were scored for viability. Embryonic survival at each dose was normalized using the survival at the mock dose. Each point corresponds to the average of eggs laid by 30–50 worms plated on 3–4 plates. Error bars represent the standard deviation between plates.