Table 1. Anti-TNF therapy increases monocyte and granulocyte numbers in lymph nodes efferent to arthritic joints in TNF-Tg mice.

PLN from the TNF-Tg mice described in Figure 1 were harvested after 6-weeks of treatment, and analyzed by flow cytometry to quantify cells per PLN, which are presented as the mean ± SEM ×10⁶ cells per PLN (* p<0.05 by unpaired t-test).

	IgG treated	Anti-TNF treated	p-value
B cells (CD19+)	1.4 ± 0.3	2.4 ± 0.8	n.s.
T cells (CD3+)	0.5 ± 0.09	2.0 ± 0.7	n.s.
non-B/non-T (CD19−, CD3−)	1.8 ± 0.3	5.2 ± 1.0	0.009
monocytes/macrophages (CD3−, CD19−, CD11b+, CD11c−, F4/80+)	0.8 ± 0.1	1.7 ± 0.4	0.047
granulocytes (CD3−, CD19−, CD11b+, CD11c−, F4/80−, Gr1+)	0.7 ± 0.09	2.0 ± 0.05	0.024