Table 2.
Prior obstetric history of 430 women with births ≤ 35 weeks and recurrence rates after 17-OHPC treatment compared to an historical cohort of 5,787 women with prior preterm birth at Parkland Hospital.
| No 17-OHPC | 17-OHPC treated | P-valueᵻ | |||
|---|---|---|---|---|---|
| Prior birth < 35 weeks | Historical cohort recurrence rate* | No. women | Recurrence | ||
| No. women | Rate | ||||
| Overall | 16.8% | 430 | 106 | 25% | 1.0 |
| Para 1 | 18% | 141 | 44 | 31% | 1.0 |
| Para 2: Both ≤ 35 weeks Only 2nd birth ≤ 35 weeks Only 1st birth ≤ 35 weeks |
43% 17% 11% |
48 52 39 |
20 11 2 |
42% 21% 5% |
0.49 0.84 0.18 |
| Para 3+: All ≤ 35 weeks Other sequences of ≤ 35 weeks |
45% 12% |
27 123 |
12 17 |
44% 14% |
0.56 0.78 |
*
Recurrence rate is derived from the Parkland Obstetric population for 1988–2011 prior to introduction of 17-OHPC.
ᵻ
P-values are one-sided