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. Author manuscript; available in PMC: 2018 Aug 1.
Published in final edited form as: Addict Behav. 2017 Feb 10;71:18–24. doi: 10.1016/j.addbeh.2017.02.018

Figure 3.

Figure 3

Withdrawal symptom severity when subjects received nicotine lozenge after stress exposure (i.e., control) and when subjects received nicotine lozenge immediately before (panel 1), 10 minutes (panel 2), 20 minutes (panel 3), and 30 minutes (panel 4) before speech. The speech task occurred between time −0 and +0 with assessments prior to the stressor indicated as (−) time and those after as (+) time. p value for (z – y vs. x – w) indicates significance of difference in stress response magnitude between experimental and control condition. p value for z vs. x indicates significance of difference in post stress withdrawal symptoms severity (where the value at time −30 was subtracted from the value at time +0 to adjust for baseline) between the experimental and control condition.