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. Author manuscript; available in PMC: 2017 Jun 19.
Published in final edited form as: Immunol Cell Biol. 2016 Dec 19;95(5):454–460. doi: 10.1038/icb.2016.122

Figure 2.

Figure 2

Vaccination induced antigen specific serum IgG responses in guinea pigs. Groups (n=5–6) of guinea pigs were immunized i.n. with CpG alone (mock), rCPAF/CpG or CT-D (1×105 IFUs). Guinea pigs were rested for 4 (CpG, rCPAF/CpG) or 8 (CT-D) weeks before challenging i.vag. with 1×105 IFU of CT-D. Total serum IgG reacting with rCPAF (a) and UV-inactivated CT-D (b) was determined 2 weeks prior to (pre-challenge) and 4 weeks after (post-challenge) challenge. * p < 0.05, ** p < 0.01 (One-Way ANOVA) comparison between indicated groups. Results are presented as average ± standard deviation of endpoint titer of each group. Results are representative of two independent experiments.