Table 3.
Logistic Regression Analysis Results of pCR Rate Stratified by Precystectomy Clinical Variables
| Variable | Patients With pCR/Total | Binary LR Analysis | Multinomial LR Analysis | ||
|---|---|---|---|---|---|
| OR (95% CI) | P Value | OR (95% CI) | P Value | ||
| Age group | .035 | .059 | |||
| >62 y | 7/64 (10.9) | Ref | Ref | ||
| ≤62 y | 19/73 (26.0) | 2.76 (1.06–7.10) | 2.72 (0.96–7.66) | ||
| CIS found on TURBT | .069 | .025 | |||
| Yes | 4/42 (9.5) | Ref | Ref | ||
| No | 22/95 (23.2) | 2.86 (0.92–8.91) | 4.08 (1.19–13.98) | ||
| Variant histologic features | .559 | .710 | |||
| Yes | 10/46 (21.7) | Ref | Ref | ||
| No | 16/91 (17.6) | 0.77 (0.32–1.86) | 0.83 (0.30–2.25) | ||
| Race | .009 | .031 | |||
| White | 21/128 (16.4) | Ref | Ref | ||
| Nonwhite | 5/9 (55.6) | 6.37 (1.58–25.71) | 6.05 (1.17–31.14) | ||
| Gender | .707 | .724 | |||
| Male | 19/104 (18.3) | Ref | Ref | ||
| Female | 7/33 (21.2) | 1.20 (0.46–3.18) | 0.81 (0.26–2.54) | ||
| Clinical stage | .164 | .058 | |||
| T3-T4N+ found on TURBT | 7/54 (13.0) | Ref | Ref | ||
| T2N0 found on TURBT | 19/83 (22.9) | 1.91 (0.77–4.76) | 2.78 (0.97–7.97) | ||
| Cisplatin-containing regimen | .337 | .229 | |||
| Yes | 24/113 (21.2) | Ref | Ref | ||
| No | 2/24 (8.3) | 0.34 (0.07–1.54) | 0.38 (0.08–1.84) | ||
Data presented as n (%).
Abbreviations: CI = confidence interval; CIS = carcinoma in situ; LR = logistic regression; OR = odds ratio; pCR = pathologic complete response; Ref = reference group; TURBT = transurethral resection of bladder tumor.