Table 1.
Clinical-pathological characteristics and subtype distribution in the GEICAM 2006-03 study*.
| CT | % | ET | % | P-value | ||
|---|---|---|---|---|---|---|
| Num. | 32 | - | 31 | - | - | |
| Age (mean) | 53.7 | - | 52.3 | - | 0.596 | |
| Menopausal status | ||||||
| Pre-menopausal | 14 | 44% | 14 | 45% | 1.000 | |
| Post-menopausal | 18 | 56% | 17 | 55% | ||
| Tumor stage | ||||||
| T1 | 1 | 3% | 2 | 6% | 0.420 | |
| T2 | 23 | 72% | 25 | 81% | ||
| T3 | 8 | 25% | 4 | 13% | ||
| Mean tumor size (cm) | 4.2 | 3.8 | 0.278 | |||
| Node | ||||||
| N0 | 15 | 47% | 19 | 61% | 0.501 | |
| N1 | 16 | 50% | 11 | 35% | ||
| N2 | 1 | 3% | 1 | 3% | ||
| Grade | ||||||
| G1 | 0 | 0% | 0 | 0% | ||
| G2 | 8 | 25% | 6 | 19% | 0.862 | |
| G3 | 18 | 56% | 19 | 61% | ||
| G4 | 6 | 19% | 6 | 19% | ||
| Histological Type | ||||||
| Ductal | 26 | 81% | 26 | 84% | 1.000 | |
| Lobular | 2 | 6% | 2 | 6% | ||
| Others | 4 | 13% | 3 | 10% | ||
| Ki-67 IHC (mean) | 31.1 | 33.5 | 0.720 | |||
| Miller-Payne Response (mean) | 2.6 | 2.2 | 0.124 | |||
| PAM50 | ||||||
| Luminal A | 16 | 50% | 13 | 42% | 0.564 | |
| Luminal B | 11 | 34% | 13 | 42% | ||
| HER2-E | 0 | 0% | 1 | 3% | ||
| Basal-like | 2 | 6% | 0 | 0% | ||
| Normal-like | 3 | 9% | 4 | 13% | ||
*
CT, chemotherapy arm; ET, endocrine therapy arm.