Table 2.
Complications of SLT
| Paper | Design | Diagnosis | Number of eyes (n)/patients | Complications |
|---|---|---|---|---|
| Chadha et al. [10] | Case report | OAG | Two patients | Corneal edema secondary to herpetic stromal keratitis without known history of herpes ophthalmicus or oral ulcers prior to the SLT treatment |
| Bettis et al. [11] | Case series | Exfoliation glaucoma | Five patients | Postoperative corneal edema, corneal endothelial injuries. IOP elevation persisting weeks to months and up to 39–48 mmHg |
| Ali Aljasim et al. [15] | Retrospective case–control study | PAC/PACG, POAG | n = 59 (PAC/PACG), n = 59 (POAG) | IOP increase of 10 mmHg in 10% of PAC/PACG patients and 5% of POAG patients 1 h after SLT |
| Narayanaswamy et al. [16] | Randomized clinical trial | PAC/PACG | n = 96 (SLT), n = 99 (PGA) | IOP increase >5mmgHg in 2% of PAC/PACG patients 30–60 min following SLT |
| Zhang et al. [22] | Retrospective chart review | Silicone oil-induced glaucoma | n = 42 | IOP increase >6 mmHg of 26.2% of eyes on the same day as SLT treatment |
| De Keyser et al. [34] | Prospective randomized clinical trial | POAG/NTG/OHT | n = 132 |
SLT induced little inflammation (e.g. pain, redness, cells in anterior chamber, transient IOP spike) Transient IOP increase >5 mmHg in 3–8.5% of patients |
| Baser et al. [36] | Case report | POAG | Two patients | PAS following repeat SLT |
| Atalay et al. [37] | Retrospective chart review | POAG | n = 33 | 3–6 months following SLT, significant changes in CCT, thinnest point of cornea, and posterior corneal asphericity at 5 and 8 mm (P = 0.03, 0.01, 0.02, and 0.04, respectively) |
| Guven Yilmaz et al. [38] | Prospective study | POAG and OHT | n = 45 | 1 month following SLT, significant increase in CCT and decrease in ACV (P < 0.05); both returned to baseline at 3 months |
| Pillunat et al. [39] | Prospective case series | OAG | n = 52 | Significant increase in CH (P = 0.028) and decrease in CRF (P = 0.037); neither is significant after adjusting for IOP reduction |
| Koc et al. [40] | Prospective randomized clinical trial | POAG | n = 40 | Temporary increase in macular thickness in three quadrants, which returned to baseline at 1-month follow-up |
ACV chamber corneal volume, CCT central corneal thickness, CH corneal hysteresis, CRF corneal resistance factor, IOP intraocular pressure, NTG normal-tension glaucoma, OAG open-angle glaucoma, OHT ocular hypertension, PAC primary angle closure, PACG primary angle-closure glaucoma, PAS peripheral anterior synechiae, PGA prostaglandin, POAG primary open-angle glaucoma, SLT selective laser trabeculoplasty