Table 3.

Outcomes of each cohort in terms of PJI and nephrotoxicity rates (based on both ICD-9 coding and elevations in serum creatinine)

Outcomes	Underdosed (n = 1130)	Adequately dosed (n = 518)	Overdosed (n = 180)	p value
PJI rate	1.77% (20)	1.74% (9)	1.67% (3)	0.995
Nephrotoxicity rate (ICD-9 coding)	1.06% (12)	0.97% (5)	2.22% (4)	0.363
AKI rate (1.5 × preoperative serum Cr or elevation by 0.3)	2.48% (28)	1.93% (10)	3.33% (6)	0.561

PJI = periprosthetic joint infection; ICD-9 = International Classification of Diseases, 9th Revision; AKI = acute kidney injury; Cr = creatinine.