Table 1.
Minimum containment level 3 (CL-3) facility verification requirements (http://www.emerge.rki.eu/Emerge/EN/Content/Topics/Rules/ECL_Biorisk.pdf?__blob=publicationFile).
| Minimum facility verification requirements (annual or regular control) | Critical equipment that should be operational and regularly test in case of power failure | Changes for which retesting may be required |
|---|---|---|
| Differential pressure | Primary or secondary containment | Replacement of CL-3 fans, duct, air valves |
| Air flow | Communication system | Replacement or repair of control wiring |
| Air flow turnover | Access security systems and limitations | Changes in building control sequences |
| High-efficiency particulate air filter certified (photometric control filters in the extraction) | Respirators, space suits | Structural changes |
| Environmental parameters (noise, temperature, humidity, lighting) | Sensors, alarms | Frequent failures of HVAC system/inoperable HVAC alarms |
| Supply exhaust interlocking system failure/reversals of airflow under normal conditions | ||
| Autoclaves and other pressure vessels | ||
| Standby power and UPS systems | ||
| Operation of interlocking doors | ||
| Operation of decontamination systems (e.g., autoclaves, fumigation chambers, liquid effluent) | ||
| Liquid effluent treatment systems | ||
| Battery driven emergency lights |