FIGURE 2.

Summary of results from microcalorimetric titrations of PcaY_PP-LBD with different ligands. Shown are structures and the corresponding K_D values as determined by ITC. The gray shading indicates the capacity to support growth of KT2440 as sole carbon source. Data are means and standard deviations from three experiments. Asterisks indicate that it is a natural compound according to the Zinc database (Irwin et al., 2012). For further information on these compounds see Supplementary Table 3.