Table 4.
Effects of iron limitation on the transcriptome of B. breve UCC2003.
| Locus tag | Gene name and/or predicted Function | Upregulation |
|---|---|---|
| Bbr_0579 | Solute binding protein of ABC transporter system, iron siderophore, metallic cations | 7.8 |
| Bbr_0268 | silP, Cation transport ATPase | 6.7 |
| Bbr_0222 | bfeO, high affinity Fe2+ periplasmic transporter | 3.7 |
| Bbr_0826 | SAM-dependent methyltransferase | 3.3 |
| Bbr_0221 | bfeU, high-affinity Fe2+ permease | 2.4 |
| Bbr_1850 | NADPH-dependent FMN reductase/Oxygen-insensitive NADPH nitroreductase | 2.4 |
| Bbr_0269 | csoR, transcriptional regulator (copper-sensitive operon repressor) | 2.1 |
| Bbr_1817 | oppB, permease protein of iron siderophore uptake system | 1.9 |
| Bbr_0223 | sifA, hypothetical protein, possible siderophore binding protein | 1.8 |
| Bbr_0750 | ATP-binding protein of ABC transporter system for metals | 1.8 |
| Bbr_0827 | Hypothetical protein, containing cupin domain | 1.8 |
| Bbr_0225 | sifC, permease protein ABC transporter ferric iron/siderophore uptake | 1.7 |
| Bbr_0224 | sifB, permease protein ABC transporter ferric iron/siderophore uptake | 1.7 |
| Bbr_1815 | oppD, ATP-binding protein of iron siderophore uptake system | 1.7 |
| Locus tag | Gene name and/or predicted Function | Downregulation |
| Bbr_1898 | nrdF, Ribonucleoside-diphosphate reductase beta chain | 4.8 |
| Bbr_1899 | nrdE, Ribonucleoside-diphosphate reductase alpha chain | 4.2 |
| Bbr_1104 | tsf, Protein Translation Elongation Factor Ts (EF-Ts) | 3.4 |
| Bbr_1582 | Narrowly conserved hypothetical membrane spanning protein | 2.6 |
| Bbr_0329 | atpD, ATP synthase beta chain | 2.5 |
| Bbr_1446 | nrdG, Anaerobic ribonucleoside-triphosphate reductase activating protein | 2.4 |
| Bbr_1622 | rplO, 50S ribosomal protein L15 | 2.3 |
| Bbr_1627 | rpsH, 30S ribosomal protein S8 | 2.3 |
| Bbr_1726 | rlpA, LSU ribosomal protein L1P | 2.3 |
| Bbr_1623 | rpmD, 50S ribosomal protein L30 | 2.2 |
| Bbr_1628 | rpsN, 30S ribosomal protein S14-1 | 2.2 |
| Bbr_1626 | rplF, 50S ribosomal protein L6 | 2.2 |
| Bbr_1624 | rpsE, 30S ribosomal protein S5 | 2.2 |
| Bbr_1583 | Histidine kinase sensor of two component system | 2.1 |
| Bbr_1632 | rpsQ, 30S ribosomal protein | 2.1 |
| Bbr_1675 | rplL, LSU ribosomal protein L12P (L7/L12) | 2.1 |
| Bbr_1581 | Narrowly conserved hypothetical membrane spanning protein | 2.1 |
| Bbr_0899 | Endonuclease involved in recombination | 2.1 |
| Bbr_0843 | Conserved hypothetical secreted protein with excalibur domain | 2.1 |
| Bbr_0925 | Permease MFS superfamily | 2.0 |