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. 2017 May 31;8:335. doi: 10.3389/fphys.2017.00335

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Copyright © 2017 Uslusoy, Nazıroğlu and Çiğ.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Effects of Hypericum perforatum (HP) on the PARP-1, caspase 3 and 9 expression levels in sciatic nerve (A,C), DRGN (B,C), skin (D,F) and muscle (Musculus piriformis) (E,F) and skin (F) of rats with SNI (mean ± SD and n = 3). Anti-β-actin was used as an internal control for the concentration of PARP1, caspase 3 and 9. Values expressed as fold increase (experimental/control). Sciatic nerve DRGN neurons were dissected from control, SNI and HP treated animals. (^ap ≤ 0.05 vs. control, sham, sham+HP groups. ^bp ≤ 0.05 and ^cp ≤ 0.001 vs. SNI group).