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. 2017 May 23;5(10):e13277. doi: 10.14814/phy2.13277

Figure 4.

Figure 4

Effects of ACE1 knockdown in the MnPO on changes of heart rate (A), respiratory rate (B), activity (C) produced by CIH during the intermittent hypoxia exposure during the light phase (left column, white backgrounds) and the normoxic dark phase (right column, grey backgrounds). A: + is ACE1 CIH Miss group different from the normoxic control groups during intermittent hypoxia. For the dark period, + is all CIH groups different from normoxic control groups (P < 0.05). B: * is significantly different from all other groups during the intermittent hypoxia period (P < 0.05). + is both CIH treatment groups significantly different from both bormoxic control groups during the intermittent hypoxia period (P < 0.05). C: There were no significant differences in activity among the groups during either time period.