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. 2017 Mar 9;45(10):5739–5756. doi: 10.1093/nar/gkx163

Figure 6.

Figure 6.

Summarizing model showing the mechanisms affected by ICF1-specific DNMT3B dysfunction in the regulation of (A) alternate isoform-TSS usage, (B) cryptic transcription, (C) sense–antisense gene self-regulatory circuit and (D) alternative exon splicing.