Table 2. Pseudomitotic index of topo II-transfected HTETOP cells in the presence or absence of Tet.
Topo II-transfected HTETOP cell line | Pseudomitotic index | |
---|---|---|
Tet (+) | Tet (-) | |
WT topo IIα | 41.03 ± 3.98 | 42.77 ± 1.57 |
C-del topo IIα | 8.32 ± 5.96 | 7.78 ± 3.93 |
Y640F topo IIα | 86.15 ± 22.99 | 44.61 ± 4.27 |
WT topo IIβ | 20.01 ± 1.11 | 12.50 ± 5.6 |
C-del topo IIβ | 30.66 ± 2.17 | 29.85 ± 1.78 |
Y656F topo IIβ | 66.33 ± 16.47 | 39.37 ± 10.54 |