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. 2017 May 2;45(10):5653–5665. doi: 10.1093/nar/gkx331

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© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 5. — The genetic effect of rs1056984 in ceRNA regulation for EUR population. (A) Hybridization pattern between miR-296-5p and binding site of DIDO1 on derived allele A. (B) Hybridization pattern between miR-296-5p and binding site of DIDO1 on ancestral allele G. (C) Boxplot of gene expression of DIDO1 on different genotype. (D) Boxplot of gene expression of TNFAIP8L1 on different genotypes. (E) The gene expression correlation of DIDO1 and TNFAIP8L1 under different genotypes. (F) Schematic diagram for rs1056984 affecting ceRNA competition under different alleles, it impacts the expression of tumor suppressor and oncogene in a reciprocal and coordinate manner. MFE: minimum free energy.