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. 2017 Mar 15;45(10):6194–6208. doi: 10.1093/nar/gkx180

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© The Author(s) 2017. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 6. — Model depicting how SINE ncRNA-mRNA intermolecular interactions facilitate an mRNA export block. SINE loci are transcriptionally activated in response to many stresses. Antisense transcribed SINEs generate RNAs with the potential to base pair with complementary SINE sequences within mRNA. SINE ncRNA–mRNA intermolecular interactions recruit the protein p54nrb, leading to a block in mRNA export.