Table 2.

Ability of biomarkers to predict cCR and pCR

Biomarker	cCR AUC	pCR AUC
Pre-CRT neutrophils	0.421	0.591
Pre-CRT lymphocytes	0.432	0.588
Pre-CRT NLR	0.521	0.503
Post-CRT neutrophils	0.536	0.506
Post-CRT lymphocytes	0.618	0.506
Post-CRT NLR	0.436	0.567
Pre-CRT monocytes	0.439	0.506
Pre-CRT haemoglobin	0.673	0.614
Pre-CRT PLR	0.436	0.387
Pre-CRT CEA	0.304	–

AUC = area under the curve; cCR = clinical complete response; CEA = carcinoembryonic antigen; CRT = chemoradiotherapy; NLR = neutrophil-to-lymphocyte ratio; pCR = pathological complete response; PLR = platelet-to-lymphocyte ratio