Table 1.
The experimental groups and the number of mice sacrificed at each time point.
| Group | Time intervals | ||||||
|---|---|---|---|---|---|---|---|
| 1 day | 4 days | 8 days | 11 days | 14 days | 85 days | ||
| Number of mice | |||||||
| (1) Negative control group | Skin | 2 | |||||
| (2) Positive control group | Skin + LPS | 2 | 2 | 2 | 0 | 2 | 0 |
| (3) Control group: H2O | Tumors + endotoxin-free water application | 6 | 6 | 5 | 0 | 0 | 0 |
| (4) Control group: H2O + EP | Tumors + endotoxin-free water application + EP pulses |
6 | 6 | 6 | 0 | 0 | 0 |
| (5) Control group: pControl + EP | Tumors + control plasmid + EP pulses | 6 | 6 | 4 | 5 | 0 | 0 |
| (5) Therapeutic group: pORF-mIL- 12-ORT + EP |
Tumors + therapeutic plasmid + EP pulses |
6 | 7 | 6 | 0 | 7 | 8 |