Figure 4.

Expression of interleukin (IL)-17 family receptors IL-17RA, RB, and RC in synoviocytes. (A) RNA was extracted from different rheumatoid arthritis synoviocyte lines (n = 8) and the expression of IL17RA, RB, and RC was assessed by qRT-PCR. Results were normalized with GAPDH expression. (B) Cells were treated for 12 h with IL-17A (50 ng/mL) and/or tumor necrosis factor alpha (0.5 ng/mL) before RNA extraction. The expression of IL17RA, RB, and RC was assessed by qRT-PCR. *p < 0.05; **p < 0.01 (Mann–Whitney non-parametric test).