Table 2.
Summary of mutations in ΦCHI14, ΦX20, and ΦCBH8 ToxINPa escape mutants.
| Escape phage | Mutation type | Gene(s) affected | Effect of mutation |
|---|---|---|---|
| ΦCHI14a | large deletion (7,647 bp) | 14 ORFs | elimination of affected genes |
| 12 tRNA genes | |||
| ΦCHI14b | nonsense mutation | asiA | E71  stop codon |
| ΦCHI14c | large deletion (10,094 bp) | 19 ORFs | elimination of affected genes |
| 13 tRNA genes | |||
| ΦCHI14e | missense mutation | orf84 | E66D |
| ΦCHI14f | deletion (10 bp) | asiA | extends protein by 17 residues |
| ΦCBH8f | large deletion (10,040 bp) | 19 ORFs | elimination of affected genes |
| 11 tRNA genes | |||
| ΦCBH8l | large deletion (7,802 bp) | 15 ORFs | elimination of affected genes |
| 11 tRNA genes | |||
| ΦCBH8m | large deletion (8,575 bp) | 17 ORFs | elimination of affected genes |
| 6 tRNA genes | |||
| ΦCBH8o | large deletion (6,521 bp) | 14 ORFs | elimination of affected genes |
| 10 tRNA genes | |||
| ΦCBH8p | large deletion (8,368 bp) | 16 ORFs | elimination of affected genes |
| 10 tRNA genes | |||
| ΦCBH8t | large deletion (7,328 bp) | 15 ORFs | elimination of affected genes |
| 9 tRNA genes | |||
| ΦCBH8u | large deletion (8,158 bp) | 17 ORFs | elimination of affected genes |
| 4 tRNA genes | |||
| ΦCBH8x | large deletion (7,731 bp) | 14 ORFs | elimination of affected genes |
| 10 tRNA genes | |||
| ΦX20b | large deletion (9,533 bp) | 19 ORFs | elimination of affected genes |
| 11 tRNA genes | |||
| ΦX20d | large deletion (9,479 bp) | 19 ORFs | elimination of affected genes |
| 8 tRNA genes | |||
| ΦX20f | large deletion (9,473 bp) | 19 ORFs | elimination of affected genes |
| 8 tRNA genes | |||
| ΦX20g | large deletion (9,533 bp) | 19 ORFs | elimination of affected genes |
| 11 tRNA genes | |||
| ΦX20h | large deletion (9533 bp) | 19 ORFs | elimination of affected genes |
| 11 tRNA genes | |||
| ΦX20j | large deletion (9,533 bp) | 19 ORFs | elimination of affected genes |
| 11 tRNA genes | |||
| ΦX20k | large deletion (9,533 bp) | 19 ORFs | elimination of affected genes |
| 11 tRNA genes | |||
| ΦX20l | large deletion (9,533 bp) | 19 ORFs | elimination of affected genes |
| 11 tRNA genes | |||
| ΦX20m | large deletion (9,533 bp) | 19 ORFs | elimination of affected genes |
| 11 tRNA genes | |||
| ΦX20n | large deletion (9,533 bp) | 19 ORFs | elimination of affected genes |
| 11 tRNA genes | |||
| ΦX20o | large deletion (9,533 bp) | 19 ORFs | elimination of affected genes |
| 11 tRNA genes |