Figure 3.

(A) Neuroanatomical distribution of apelin-IR cell bodies and nerve fibers on a parasagittal section of adult colchicine-treated rat brain. Apelin-IR cell bodies and nerve fibers are shown as dots and lines, respectively. Figure adapted from Ref. (56) with permission from the copyright holders. (B). Distribution of the rat ApelinR mRNA expression in the adult rat brain. The figures were scanned directly from the X-ray film. Shown are representative frontal sections at anteriorities determined from the bregma indicated in the lower right corner. i–iv were hybridized with the antisense ApelinR cRNA probe. Scale bar: 2 mm. Figure adapted from Ref. (2) with permission from the copyright holders. Abbreviations: Acb, nucleus accumbens; Amb, nucleus ambiguus; Amy, amygdala; AL, anterior lobe of the pituitary gland; AP, area postrema; Arc, arcuate nucleus of the hypothalamus; BST, bed nucleus of the stria terminalis; C, cerebellum; CC, corpus callosum; Cput, caudate putamen; Cx, cerebral cortex; DBB, diagonal band of Broca; DMH, dorsomedial nucleus of the hypothalamus; DR, dorsal raphe nucleus; DTg, dorsal tegmental nucleus; ENT, entorhinal cortex; HIP, hippocampus; Hpt, hypothalamus; IL, intermediate lobe of the pituitary; LC, locus coeruleus; LPO, lateral preoptic area; LRN, lateral reticular nucleus; ME, median eminence; MPO, medial preoptic nucleus; NL, neural lobe of the pituitary; NLOT, nucleus of the lateral olfactory tract; NST, nucleus of the solitary tract; OB, olfactory bulb; OVLT, vascular organ of the lamina terminalis; PAG, periaqueductal gray; PBN, parabrachial nucleus; PIN, pineal gland; PIR, piriform cortex; PVA, paraventricular thalamic nucleus; PVN, paraventricular nucleus of the hypothalamus; Re, reuniens thalamic nucleus; SCN, suprachiasmatic nucleus; SFO, subfornical organ; SN, substantia nigra; SNc, pars compacta of the substantia nigra; SON, supraoptic nucleus; Sp5, spinal trigeminal nucleus; S, septum; Th, thalamus; VMH, ventromedial nucleus of the hypothalamus.