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. 2017 Apr 3;7(32):19685–19693. doi: 10.1039/c7ra01100h

Table 2. IC50 and CI50 values of free drug and cMLVs therapeutics against OVCAR8 and NCI/ADR-RES.

Formulation CPT/PTX (molar ratio) OVCAR8
NCI/ADR-RES
IC50 (μM) CI50 IC50 (μM) CI50
CPT 21.09 79.36
PTX 5.85 9.86
CPT + PTX 1.52/1.52 0.33 7.13/7.13 0.81
cMLVs (CPT) 16.54 18.88
cMLVs (PTX) 2.69 8.44
cMLVs (4CPT + PTX) 0.92/0.23 0.14 6.05/1.51 0.49
cMLVs (CPT + PTX) 0.29/0.29 0.13 1.65/1.65 0.28
cMLVs (CPT + 4PTX) 0.16/0.63 0.24 0.93/3.73 0.50