Table 2. IC50 and CI50 values of free drug and cMLVs therapeutics against OVCAR8 and NCI/ADR-RES.
| Formulation CPT/PTX (molar ratio) | OVCAR8 |
NCI/ADR-RES |
||
| IC50 (μM) | CI50 | IC50 (μM) | CI50 | |
| CPT | 21.09 | — | 79.36 | — |
| PTX | 5.85 | — | 9.86 | — |
| CPT + PTX | 1.52/1.52 | 0.33 | 7.13/7.13 | 0.81 |
| cMLVs (CPT) | 16.54 | — | 18.88 | — |
| cMLVs (PTX) | 2.69 | — | 8.44 | — |
| cMLVs (4CPT + PTX) | 0.92/0.23 | 0.14 | 6.05/1.51 | 0.49 |
| cMLVs (CPT + PTX) | 0.29/0.29 | 0.13 | 1.65/1.65 | 0.28 |
| cMLVs (CPT + 4PTX) | 0.16/0.63 | 0.24 | 0.93/3.73 | 0.50 |