Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Potential role of Gal-1-α4 interactions in limiting eosinophil trafficking and recruitment. In a wild-type setting, Gal-1 interacts with α4, causes cell clustering, increased adhesion in inflamed blood vessels resulting in restricted chemokine-induced migration. In the absence of Gal-1, eosinophils exhibit decreased adhesion in inflamed blood vessels and increased chemokine-induced migration to extravascular sites of inflammation.
