Table 1.

Indications for Combined Heart–Liver Transplantation (CHLT) As Reported in the Literature.

Indication for Combined Heart–Liver Transplantation
Familial amyloidosis [5–10,12,14,15,30,34,35,52]
Familial hypercholesterolemia [1,2,17,19,21,35]
Homozygous beta-thalassemia [19,35]
Hemochromatosis [5,8,15,27,35,53]
Alcoholic cardiomyopathy [35]
Cryptogenic cirrhosis with underlying cardiomyopathy [35]
Glycogen storage disease [8]
Indications for Heart Portion	Indications for Liver Portion
failure of single ventricle variations of congenital heart disease [22–25,40]	congestive hepatopathy or cardiac cirrhosis [5–8,15,22–24,29,31,36,37,40,54]
congenital heart disease [5,7,8,15,31]	hepatitis C [5,6,8,31,35,37,42]
idiopathic restrictive cardiomyopathy [5,7,8]	cryptogenic cirrhosis [5,6,8,33,35,38,44,55]
restrictive cardiomyopathy[15,37]	alcoholic cirrhosis [5,6,8,33,36,44,56]
arrhythmogenic right ventricular dysplasia [7]	chronic hepatitis — other [5]
coronary artery disease [8]	acute hepatic failure [5]
nonischemic cardiomyopathy [29,31]	primary biliary cirrhosis [5,6,8,15]
ischemic cardiomyopathy [31,33,36,37]	primary sclerosing cholangitis [5,6,8]
idiopathic cardiomyopathy [2,44]	biliary atresia/hypoplasia [2,5]
alcoholic cardiomyopathy [8,35]	metabolic disease – other [5]
viral dilated cardiomyopathy [8]	cirrhosis — other [5,25]
idiopathic dilated cardiomyopathy [5,8]	Carcinoid [5]
ischemic dilated cardiomyopathy [5]	cystic fibrosis [5]
alcoholic dilated cardiomyopathy [5]	Budd–Chiari syndrome [5,8]
dilated cardiomyopathy [33,36,37,42,44,56]	unknown [5]
apical variant hypertrophic cardiomyopathy [7]	alpha 1-antitrypsin [6,8,31]
hypertrophic cardiomyopathy [5,37,38]	autoimmune hepatitis [8]
valvular disease [5,8,35]	nodular regenerative hyperplasia [8]
primary pulmonary hypertension [5,15]
glycogen storage disease [5]
cystic fibrosis [5]
sarcoidosis [5]
unknown [5]