Table 2.

Differentially expressed MicroRNAs comparing upper lung and lower lung AM

microRNA ID	Expression change	logFC	P value
Normoxia
Upper vs. lowera
hsa-miR-30e-5p	Increase	0.313	0.018
hsa-miR-4454	Decrease	−0.986	0.032
hsa-miR-4443	Decrease	−0.757	0.003
Hypoxia
Upper lobe MOb
hsa-miR-664a-3p	Decrease	−0.498	0.005
Lower lobe MOb
hsa-miR-30e-5p	Increase	0.412	0.015
hsa-miR-93-5p	Increase	0.306	0.036
hsa-miR-4454	Decrease	−1.057	0.019
hsa-miR-22-3p	Decrease	−0.540	0.007

microRNA ID = official microRNA name according to miRBASE v21; logFC = log2 fold change in macrophages from upper lobe vs. lower lobe

P value = the unadjusted P value from the statistical test (paired analysis)

^aUpper lobe AM vs. lower lobe AM

^b21%O₂ vs. 5% O₂