Table 4.

The effects of NPs on the developmental competence of immature porcine oocytes from 3–8 mm follicles (mean ± S. E. M.)

	oocytes(n)	cleaved oocytes (%)	blastocysts (%)
Control	305	36.0 ± 1.9	10.2 ± 2.6
cilostamide	318	36.9 ± 2.6	11.4 ± 3.3
BNP	369	36.6 ± 3.8	9.8 ± 1.7
CNP	256	37.2 ± 1.6	11.6 ± 3.6

Cleavage rates on day 2 and Blastocyst developmental rates on day 7 after IVF of the COCs recovered from the 3.0 - 8.0 mm follicles in standard IVM for 46 h (as negative controls), or pre-cultured with PMCI–cilostamide 20 h plus IVM 46 h (as positive controls) and pre-cultured with PMCI–BNP/CNP 20 h plus IVM 46 h (as experimental groups)