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. 2017 May 17;2017:6761719. doi: 10.1155/2017/6761719

Table 3.

Analysis of variance.

Source Sum of squares Degrees of freedom Mean of square F value P value
Yield of extraction

Model 321.42 14 22.96 10.37 <0.0001 (significant)
Residual 31.00 14 2.21
Pure error 1.17 4 0.29
Lack of fit 29.83 10 2.98 10.24 0.0192
Total 352.41 28
R 2 0.9120 Adj. R2 0.8241

Model equation Y1 = 38.94 − 0.77X1 + 1.48X2 + 3.75X3 − 0.23X4 + 0.19X1X2 − 0.97X1X3 + 1.28X1X4 + 0.36X2X3 − 1.38X2X4 + 0.063X3X4 − 2.81X12 − 1.62X22 − 3.12X32 − 0.73X42

Total polyphenol content

Model 423.50 14 30.25 47.38 <0.0001 (significant)
Residual 8.94 14 0.64
Pure error 2.49 4 0.62
Lack of fit 6.45 10 0.65 1.04 0.5314 (not significant)
Total 432.42 28
R 2 0.9793 Adj. R2 0.9587

Model equation Y2 = 47.69 + 0.27X1 − 0.42X2 + 2.13X3 − 1.22X4 + 0.62X1X2 − 2.51X1X3 + 0.13X1X4 − 2.90X2X3 − 0.090X2X4 − 3.38X3X4 − 0.75X12 + 0.43X22 − 5.83X32 − 1.73X42

PTP-1B inhibition rate

Model 1318.42 14 94.17 9.82 <0.0001 (significant)
Residual 134.24 14 4.41
Pure error 31.82 4 7.95
Lack of fit 102.42 10 10.24 1.29 0.4350 (not significant)
Total 1452.66 28
R 2 0.9076 Adj. R2 0.8152

Model equation Y3 = 86.12 − 1.73X1 + 2.89X2 − 2.24X3 + 2.37X4 − 0.13X1X2 + 1.94X1X3 − 2.66X1X4 − 1.44X2X3 + 4.37X2X4 − 5.86X3X4 − 3.95X12 − 2.36X22 − 2.66X32 − 10.86X42

α-Glucosidase inhibition rate

Model 1449.06 14 103.50 10.43 <0.0001 (significant)
Residual 138.87 14 9.92
Pure error 11.50 4 2.88
Lack of fit 127.37 10 12.74 4.43 0.0822 (not significant)
Total 1587.93 28
R 2 0.9125 Adj. R2 0.8251

Model equation Y4 = 96.63 + 1.04X1 − 2.99X2 − 0.79X3 + 2.06X4 + 10.73X1X2 + 1.50X1X3 − 6.73X1X4 + 0.42X2X3 − 1.70X2X4 + 4.42X3X4 − 0.98X12 − 7.58X22 − 1.73X32 − 4.66X42

ABTS inhibition rate

Model 2213.57 14 158.11 33.37 <0.0001 (significant)
Residual 66.33 14 4.74
Pure error 8.87 4 2.22
Lack of fit 57.46 10 5.75 2.59 0.1859 (not significant)
Total 2279.90 28
R 2 0.9709 Adj. R2 0.9418

Model equation Y5 = 75.91 + 2.73X1 + 3.70X2 + 4.64X3 − 1.43X4 + 8.08X1X2 + 5.21X1X3 + 4.05X1X4 + 1.48X2X3 + 3.08X2X4 + 6.83X3X4 − 2.12X12 − 11.41X22 − 6.20X32 − 7.65X42

Value of lack of fit as analyzed by ANOVA.