Fig. 3.
Aberrant localisation of AZ proteins in NMJs of adult integrin-α3+/− mice. Immunofluorescence staining for AZ proteins bassoon (Bssn; A,D), piccolo (Picc; B,E) and P/Q VGCC (C,F) in WT (A-C) and integrin-α3+/− (D-F) sternomastoid muscles at 2 months. Fluorescence intensities were quantified in each genotype for bassoon (G), piccolo (H) and P/Q VGCC (I) from 8-13 NMJs across three animals/genotype. Data points for each animal plotted with median indicated by a line; f.u., fluorescence units. Scale bars: 10 μm.