Fig. 6.

Inhibition of Hsp90α suppressed RhoA activity and MLC phosphorylation. a Pretreated with 1G6-D7 (30 μg/ml) for 2 h, cells were exposed to HDM (400 U/ml) for 24 h. MLC and p-MLC were detected. b and c Sh-Hsp90α cells were exposed to HDM (400 U/ml) for 24 h. the activity of RhoA and the phosphorylation of MLC were measured respectively. Data are mean ± SD of three independent experiments.^* P < 0.05 versus con group; ^# P < 0.05 versus HDM group