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Characteristics of the three PDXs used
| PDX ID | DIAGNOSIS | TP53 status | IHC | ||
|---|---|---|---|---|---|
| PTEN | NF1 | p-ERK | |||
| MNHOC124 | Serous/endometroid | mut | - | ++ | +++ |
| MNHOC218 | Endometroid | mut | - | + | ++ |
| MNHOC239 | Serous | mut | - | ++ | ++ |
IHC Immunoistochemistry. Protein expression was cytoplasmic with no nuclear or membrane-associated staining. The intensity of the staining has been ranked according to the following scale: - negative; +/- slight/doubtful; + slight; ++ moderate; +++ marked
Mut: mutated
