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. 2017 Mar 16;6(5):688–697. doi: 10.1242/bio.024653

Fig. 3.

Fig. 3.

Microbead-induced pulmonary microthrombosis increases tumour formation in a temporal manner. (A) Representative lung sections stained with H&E following intravenous injection of vehicle or microbeads given 1 day prior (−1), at the same time (0), or 1 day after (+1) intravenous LLCs. (B) Number and (C) area of pulmonary tumours following intravenous microbead administration at different times with respect to intravenous injection of LLCs. (D) Number of tumour microbeads, and (E) microthrombi size. Mice were culled at day 14 post-LLCs. N=5/group. *P<0.05, ***P<0.001, and ****P<0.0001 versus vehicle-treated controls; #P<0.05 versus days −5, −1, and 0; *, ***, and ****: unpaired two-tailed Student t-tests. #: ANOVA with Bonferroni post-test. Means±s.e.