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. 2016 Dec;57(12):1858–1864. doi: 10.2967/jnumed.116.176206

TABLE 2.

Absorbed Radiation Dose Estimates (mGy/MBq) of 89Zr-IAb2M to Organs

All patients
Target organ Mean Minimum to maximum Cohort I mean Cohort II mean Cohort III mean
Adrenals 0.53 (0.06) 0.43–0.67 0.51 (0.05) 0.57 (0.08) 0.52 (0.05)
Brain 0.17 (0.04) 0.11–0.24 0.15 (0.03) 0.17 (0.04) 0.19 (0.03)
Breasts 0.22 (0.03) 0.17–0.28 0.21 (0.03) 0.23 (0.04) 0.24 (0.03)
Gallbladder wall 0.73 (0.11) 0.52–0.94 0.71 (0.11) 0.81 (0.11) 0.68 (0.09)
Lower large intestine wall 0.49 (0.13) 0.29–0.74 0.51 (0.15) 0.49 (0.13) 0.48 (0.14)
Small intestine 0.36 (0.06) 0.26–0.46 0.34 (0.06) 0.37 (0.07) 0.36 (0.05)
Stomach wall 0.35 (0.05) 0.27–0.43 0.33 (0.04) 0.36 (0.06) 0.36 (0.04)
Upper large intestine wall 0.45 (0.08) 0.31–0.58 0.45 (0.09) 0.46 (0.09) 0.44 (0.09)
Heart wall 0.69 (0.09) 0.52–0.85 0.63 (0.06) 0.70 (0.12) 0.74 (0.04)
Kidneys 1.36 (0.26) 1.02–1.87 1.30 (0.23) 1.53 (0.29) 1.26 (0.18)
Liver 1.67 (0.3) 0.99–2.34 1.71 (0.24) 1.83 (0.32) 1.46 (0.24)
Lungs 0.52 (0.08) 0.39–0.71 0.53 (0.05) 0.52 (0.11) 0.50 (0.08)
Muscle 0.25 (0.04) 0.19–0.33 0.23 (0.03) 0.26 (0.05) 0.27 (0.03)
Pancreas 0.5 (0.06) 0.4–0.63 0.47 (0.05) 0.52 (0.08) 0.50 (0.04)
Red marrow 0.32 (0.05) 0.23–0.41 0.29 (0.04) 0.33 (0.07) 0.34 (0.04)
Osteogenic cells 0.34 (0.07) 0.23–0.46 0.30 (0.05) 0.35 (0.09) 0.36 (0.06)
Skin 0.17 (0.03) 0.12–0.23 0.16 (0.03) 0.18 (0.04) 0.18 (0.03)
Spleen 0.76 (0.16) 0.49–1.14 0.71 (0.10) 0.76 (0.25) 0.80 (0.08)
Testes 0.19 (0.04) 0.13–0.27 0.17 (0.04) 0.19 (0.05) 0.21 (0.04)
Thymus 0.31 (0.05) 0.22–0.39 0.28 (0.03) 0.31 (0.06) 0.33 (0.04)
Thyroid 0.21 (0.04) 0.15–0.3 0.19 (0.04) 0.22 (0.05) 0.24 (0.04)
Urinary bladder wall 0.25 (0.05) 0.18–0.36 0.23 (0.04) 0.26 (0.06) 0.28 (0.04)
Total body 0.3 (0.04) 0.23–0.37 0.28 (0.04) 0.31 (0.05) 0.31 (0.04)
Effective dose equivalent (mSv/MBq) 0.54 (0.07) 0.43–0.68 0.52 (0.05) 0.57 (0.09) 0.53 (0.04)
Effective dose (mSv/MBq) 0.41 (0.06) 0.3–0.51 0.40 (0.05) 0.43 (0.08) 0.41 (0.04)