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. 2017 May 30;17:388. doi: 10.1186/s12885-017-3378-2

Table 3.

MBL codon 54 G > A polymorphism and the risk of gastroduodenal diseases

Genotype Disease group Unadjusted OR (95% CI) by univariate analysis p Adjusted OR (95% CI) by multivariate analysis p
G/A (heterozygote) Hp(+) NAG (n = 49) 0.93 (0.56–1.55) 0.7828 1.02 (0.59–1.75) 0.9466
Hp(+) mild AG (n = 27) 1.24 (0.66–2.34) 0.5074 1.16 (0.60–2.26) 0.6527
Hp(+) severe AG (n = 37) 1.38 (0.76–2.52) 0.2937 1.16 (0.61–2.18) 0.6498
Hp(−) DU(n = 3) 1.23 (0.27–5.66) 0.7938 1.21 (0.26–5.71) 0.8082
Hp(+) DU (n = 73) 1.19 (0.76–1.85) 0.4450 1.24 (0.78–1.99) 0.3605
Hp(−) GC(n = 46) 1.16 (0.65–2.04) 0.6170 1.11 (0.61–2.00) 0.7356
Hp(+) GC (n = 122) 0.85 (0.55–1.31) 0.4566 0.85 (0.54–1.34) 0.7356
A/A (mutant) Hp(+) NAG (n = 7) 0.95 (0.33–2.74) 0.9255 1.19 (0.39–3.61) 0.7561
Hp(+) mild AG (n = 5) 0.36 (0.04–2.89) 0.3332 0.33 (0.04–2.81) 0.3126
Hp(+) severe AG (n = 9) 0.64 (0.13–3.09) 0.5822 0.61 (0.12–3.12) 0.5560
Hp(−) DU (n = 1) 1.25(0.32–5.88) 0.9521 1.24(0.31–5.77) 0.9434
Hp(+) DU (n = 14) 0.43 (0.13–1.43) 0.1697 0.45 (0.13–1.55) 0.2031
Hp(−) GC (n = 7) 1.51 (0.52–4.42) 0.4543 1.93 (0.63–5.89) 0.2484
Hp(+) GC (n = 27) 0.88 (0.36–2.15) 0.7762 1.10 (0.43–2.79) 0.8496
G/A + A/A (A carrier) Hp(+) NAG (n = 56) 0.93 (0.57–1.52) 0.7820 1.04 (0.62–1.75) 0.8774
Hp(+) mild AG (n = 32) 1.12 (0.60–2.09) 0.7239 1.05 (0.55–2.00) 0.8893
Hp(+) severe AG (n = 46) 1.28 (0.71–2.29) 0.4103 1.09 (0.59–2.01) 0.7929
Hp(−) DU (n = 4) 1.06 (0.23–4.87) 0.9421 1.06 (0.23–4.98) 0.9386
Hp(+) DU (n = 87) 1.08 (0.71–1.66) 0.7110 1.13 (0.72–1.78) 0.5868
Hp(−) GC (n = 53) 1.20 (0.70–2.07) 0.5008 1.19 (0.68–2.09) 0.5480
Hp(+) GC (n = 149) 0.85 (0.57–1.29) 0.4488 0.88 (0.57–1.35) 0.5528

The control was regarded as the reference subject group, and the G/G wild type was considered as the reference genotype