Table 2.
Meta-analysis of associations between IL23R polymorphisms and overall uveitis
| Polymorphism | Test of association | Test of heterogeneity | |||||
|---|---|---|---|---|---|---|---|
| OR | 95% CI | P-value | Model | P-value | I2(%) | ||
| rs7517847 | G vs. T | 1.01 | 0.92–1.12 | 0.83 | F | 0.14 | 40 |
| GG vs. GT + TT | 0.70 | 0.40–1.21 | 0.20 | R | 0.00003 | 81 | |
| GG + GT vs. TT | 0.92 | 0.80–1.07 | 0.29 | F | 0.20 | 32 | |
| GG vs. TT | 0.88 | 0.65–1.19 | 0.41 | R | 0.06 | 53 | |
| rs17375018 | A vs. G | 0.68 | 0.47–0.99 | 0.05 | R | <0.00001 | 87 |
| AA vs. AG + GG | 0.76 | 0.49–1.18 | 0.22 | R | 0.09 | 50 | |
| AA + AG vs. GG | 0.59 | 0.35–0.99 | 0.04 | R | <0.00001 | 88 | |
| AA vs. GG | 0.56 | 0.29–1.09 | 0.09 | R | 0.003 | 75 | |
| rs11209032 | A vs. G | 1.20 | 0.87–1.64 | 0.27 | R | <0.0001 | 86 |
| AA vs. AG + GG | 1.33 | 1.11–1.60 | 0.002 | F | 0.07 | 54 | |
| AA + AG vs. GG | 1.13 | 0.82–1.56 | 0.45 | R | 0.03 | 64 | |
| AA vs. GG | 1.34 | 0.85–2.12 | 0.20 | R | 0.007 | 71 | |
R random effects model, F fixed effects model