Table 3.
Meta-analysis of associations between IL23R polymorphisms and uveitis without Fuchs’ syndrome
| Polymorphism | Test of association | Test of heterogeneity | |||||
|---|---|---|---|---|---|---|---|
| OR | 95% CI | P-value | Model | P-value | I2(%) | ||
| rs7517847 | G vs. T | 0.99 | 0.84–1.16 | 0.87 | R | 0.08 | 51 |
| GG vs. GT + TT | 0.59 | 0.31–1.13 | 0.11 | R | 0.0007 | 82 | |
| GG + GT vs. TT | 0.94 | 0.81–1.10 | 0.46 | F | 0.14 | 42 | |
| GG vs. TT | 0.84 | 0.59–1.22 | 0.36 | R | 0.03 | 61 | |
| rs17375018 | A vs. G | 0.64 | 0.40–1.04 | 0.07 | R | <0.00001 | 90 |
| AA vs. AG + GG | 0.76 | 0.43–1.33 | 0.34 | R | 0.05 | 61 | |
| AA + AG vs. GG | 0.54 | 0.28–1.04 | 0.06 | R | <0.00001 | 91 | |
| AA vs. GG | 0.54 | 0.23–1.25 | 0.15 | R | 0.001 | 81 | |
| rs11209032 | A vs. G | 1.13 | 0.76–1.69 | 0.54 | R | <0.0001 | 89 |
| AA vs. AG + GG | 1.21 | 0.88–1.65 | 0.24 | R | 0.11 | 50 | |
| AA + AG vs. GG | 1.07 | 0.72–1.58 | 0.75 | R | 0.02 | 71 | |
| AA vs. GG | 1.19 | 0.69–2.06 | 0.52 | R | 0.009 | 74 | |
R random effects model, F fixed effects model