Table 3.
Causes of death after TB treatment initiation, n = 310, INI-Fiocruz cohort, 2000–2010
| Underlying cause of death; n (%) | Immediate cause of death; n (%) | Contributing cause of deatha; n | ||||||
|---|---|---|---|---|---|---|---|---|
| ≤ 90 days N = 21 |
> 90 days N = 43 |
≤ 90 days N = 21 |
> 90 days N = 43 |
≤ 90 days | > 90 days | |||
| Aids | 18 (85.72) | 30 (69.80) | Invasive bacterial disease | 11 (52.38) | 19 (44.20) | Tuberculosis | 12 | 15 |
| Invasive bacterial disease | 1 (4.76) | 1 (2.30) | Aids | 4 (19.04) | 6 (14.00) | Aids | 9 | 18 |
| Renal failure | 0 | 2 (4.70) | Tuberculosis | 3 (14.30) | 6 (14.00) | Invasive bacterial disease | 4 | 2 |
| Hepatic cirrhosis | 1 (4.76) | 0 | Acute coronary disease | 0 | 1 (2.30) | IRIS | 1 | 2 |
| Hepatitis C, chronic | 1 (2.30) | Heart failure | 0 | 1 (2.30) | Renal failure | 1 | 1 | |
| Heart failure | 0 | 1 (2.30) | Renal failure | 0 | 1 (2.30) | Hepatotoxicity | 0 | 1 |
| Acute coronary disease | 0 | 1 (2.30) | Hepatic failure | 1 (4.76) | 0 | Hepatic failure | 0 | 2 |
| Chronic obstructive pulmonary disease (COPD) | 1 (2.30) | Acute respiratory distress | 0 | 1 (2.30) | Hepatitis B, chronic | 0 | 1 | |
| Depression | 0 | 1 (2.30) | Lactic acidosis | 0 | 1 (2.30) | Others | 4 | 15 |
| Violent death | 0 | 2 (4.70) | Suicide | 0 | 1 (2.30) | |||
| Drug abuse | 1 (2.30) | Violent death | 0 | 1 (2.30) | ||||
| Unknown | 1 (4.76) | 2 (4.70) | Head trauma | 0 | 1 (2.30) | |||
| Digestive hemorrhage | 1 (4.76) | 0 | ||||||
| Unknown | 1 (4.76) | 4 (9.4) | ||||||
aMore than one contributing cause of death can be reported.
IRIS: immune reconstitution inflammatory syndrome.