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. 2017 Apr 25;13(6):3239–3248. doi: 10.3892/etm.2017.4378

Table IV.

Top 15 GO functional annotations of differentially expression miRNA target genes.

GO ID GO term Count P-value FDR
Biological process
  GO:0015833 Peptide transport     2 5.21E-05 2.63E-01
  GO:0042886 Amide transport     2 5.21E-05 1.31E-01
  GO:0042327 Positive regulation of phosphorylation   19 1.13E-04 1.91E-01
  GO:0044712 Single-organism catabolic process   15 2.38E-04 3.00E-01
  GO:0010562 Positive regulation of phosphorus metabolic process   20 2.38E-04 2.40E-01
  GO:0045937 Positive regulation of phosphate metabolic process   20 2.38E-04 2.00E-01
  GO:0044763 Single-organism cellular process 320 2.73E-04 1.97E-01
  GO:0060191 Regulation of lipase activity     5 3.88E-04 2.45E-01
  GO:0030574 Collagen catabolic process     6 5.20E-04 2.92E-01
  GO:0032963 Collagen metabolic process     6 5.20E-04 2.62E-01
  GO:0044259 Multicellular organismal macromolecule metabolic process     6 5.20E-04 2.39E-01
  GO:0044243 Multicellular organismal catabolic process     6 5.20E-04 2.19E-01
  GO:0044236 Multicellular organismal metabolic process     6 5.20E-04 2.02E-01
  GO:0042325 Regulation of phosphorylation   20 6.27E-04 2.26E-01
  GO:0032924 Activin receptor signaling pathway     2 7.48E-04 2.52E-01
Cellular component
  GO:0005581 Collagen trimer     8 2.31E-05 1.29E-02
  GO:0005788 Endoplasmic reticulum lumen     7 4.65E-04 1.30E-01
Molecular function
  GO:0005524 ATP binding     7 9.26E-05 8.93E-02
  GO:0032559 Adenyl ribonucleotide binding     7 1.26E-04 6.09E-02
  GO:0030554 Adenyl nucleotide binding     7 1.26E-04 4.06E-02
  GO:0043492 ATPase activity, coupled to movement of substances     2 1.47E-04 3.53E-02
  GO:0015399 Primary active transmembrane transporter activity     2 1.47E-04 2.83E-02
  GO:0015405 P-P-bond-hydrolysis-driven transmembrane transporter activity     2 1.47E-04 2.36E-02
  GO:0016820 Hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances     2 1.47E-04 2.02E-02
  GO:0042626 ATPase activity, coupled to transmembrane movement of substances     2 1.47E-04 1.77E-02
  GO:0048185 Activin binding     2 2.69E-04 2.88E-02
  GO:0016361 Activin receptor activity, type I     2 2.69E-04 2.59E-02
  GO:0017002 Activin-activated receptor activity     2 2.69E-04 2.36E-02
  GO:0051117 ATPase binding     3 3.01E-04 2.42E-02
  GO:0019901 Protein kinase binding   12 3.39E-04 2.51E-02
  GO:0032549 Ribonucleoside binding     7 4.08E-04 2.81E-02
  GO:0032550 Purine ribonucleoside binding     7 4.08E-04 2.62E-02

GO, gene otology; FDR, false discovery rate; ATP, adenosine triphosphate.