Table 2.
Antibacterial and antifungal macrolides.
| Metabolite | Source | Location | Target | Concentration/Effect | Reference |
|---|---|---|---|---|---|
| 6-hydroxyscytophycin B (35) | Scytonema mirabile | cultured | Fungus (1) Aspergillus oryzae (2) Candida albicans (3) Penicillium notatum (4) Saccharomyces cerevisiae | nd a | [23] |
| 19-O-demethylscytophycin C (36) | Scytonema burmanicurn | cultured | Fungus (1) Aspergillus oryzae (2) Candida albicans (3) Penicillium notatum (4) Saccharomyces cerevisiae | nd a | [23] |
| 6-hydroxy-7-O-methylscytophycin E (37) | Scytonema ocellatum | cultured | Fungus (1) Aspergillus oryzae (2) Candida albicans (3) Penicillium notatum (4) Saccharomyces cerevisiae | nd a | [23] |
| tolytoxin (38) | Tolypothrix conglutinata var. colorata | Fanning Island | Fungi Penicillium notatum and Rhizoctonia solani 1165 | MIC value of 0.25 nM respectively | [24] |
| 7-OMe-scytophycin B (52) | Anabaena sp. | cultured | Fungus Candida albicans HAMBI 484 and Candida guilliermondii HAMBI 257 | MIC values of 0.40 and 0.80 mM respectively; IC50 value of 0.19 and 0.23 µM respectively | [45] |
| amantelide A (53) | Oscillatoriales | Guam | Fungi Lindra thalassiae and Fusarium sp. | totally inhibited of 62.5 μg/mL | [46] |
| amantelide B (54) | Oscillatoriales | Guam | Fungus Dendryphiella salina | totally inhibited of 6.25 μg/mL | [46] |
a Not determined.