Table 3.
Effects of cyanobacterium-derived macrolides on animals.
| Metabolite | Source | Location | Target Fauna | Impacts | Reference |
|---|---|---|---|---|---|
| lyngbyabellin A (1) | Lyngbya majuscula | Guam | mice | LD50 value of 1.2–1.5 mg/kg | [6] |
| tolytoxin (38) | Scytonema pseudohofmanni | cultured | mice | LD50 value of 1.5 mg/kg | [24] |
| sanctolide A (48) | Oscillatoria sancta | cultured | brine shrimp | LD50 value of 23.5 μM | [28] |
| gloeolactone (55) | Gloeotrichia sp. | Clark Canyon Reservoir | brine shrimp | 100% killed at 125 µg/mL | [48] |
| phormidolide (56) | Phormidium sp. | Sulawesi, Indonesia | brine shrimp | LD50 value of 1.5 μM | [49] |
| cyanolide A (57) | Lyngbya bouillonii | Papua New Guinea | snail vector Biomphalaria glabrata | LD50 value of 1.2 μM | [50] |