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Effects of (-)-4-hydroxysattabacin (4OH-ST), 1) treatment on B16F10 cells with various concentrations of conventional agents. (a) Melanin contents were measured by melanin assay; (b) Cell viability was determined by MTT assay. The cells were treated with (-)-4OH-ST (1), arbutin, or kojic acid at the indicated concentrations for 48 h; (c) Morphological changes of B16F10 cells were observed under optical microscopy (400×). Data are presented as the mean ± SD (n = 3).
