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. 2017 Apr 21;13(6):2775–2782. doi: 10.3892/etm.2017.4371

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Copyright: © Kim et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 1. — Effect of CIMT on body weight and plasma corticosterone levels. (A and B) A CIMT-treated rat, with restraint to the unaffected forelimb by wearing a pouch, forcing the use of the affected limb on a motorized treadmill. (C) Timeline of the experimental design. (D) Body weight was monitored from 3 weeks after HI injury, and measured up to 6 weeks after HI injury. Groups were as follows: HI, HI injury and non-treated group (HI/vehicle: n=12); 10, HI injury and CIMT for 10 min (n=12); 20, HI injury and CIMT for 20 min (n=12); 30, HI injury CIMT for 30 min (n=12). (E) Corticosterone concentration in plasma was determined by ELISA assay at 7 weeks after HI. *P<0.05 vs. sham group (unpaired t-test). HI, hypoxic-ischemic; CIMT, constraint-induced movement therapy.